Website Software“Reactivities of N-nitrosamines against common reagents and reaction conditions”, G. A. Hodgin, M. J. Burns, B. J. Deadman, C. S. Roberts, K. K. Hii, and B. N. Nguyen, Org. Process Res. Dev. 2024, 28, 3837–3846 article. DOI: 10.1021/acs.oprd.4c00217
“Auto-VTNA: An Automatic VTNA platform for Determination of Global Rate Equations”, D. Dalland, L. Schrecker, and K. K. Hii, Digital Discovery, 2024, 3, 2118-2129. DOI: 10.1039/D4DD00111G
“Determining Kinetics of Fast Exothermic Reactions using a Flow Calorimeter”, Z. Gulsoy, I. Dorokhov, D. Ohlig, M. Goedde, K. K. Hii, K. Hellgardt, Chem. Eng. J. 2024, 494, 153184. DOI: 10.1016/j.cej.2024.153184.
“Deconvoluting substrates, support and temperature effects on leaching and deactivation of Pd catalysts: an in-situ study in flow”, O. J. Newton, M. J. Takle, J. Richardson, K. Hellgardt and K. K. Hii, ACS Catal. 2024, 14, 9678-9686. DOI: 10.1021/acscatal.4c02028.
“Liquizald−Thermally Stable N-Nitrosamine Precursor for Diazomethane”, F. Horvath-Gerber, D. Ohlig, K. K. Hii, B. Deadman, R. P. Attrill, and K. Hellgardt, Org. Process Res. Dev. 2024, 28, 597–608. DOI: 10.1021/acs.oprd.3c00456.
“The Automated Discovery of Kinetic Rate Models - Methodological Frameworks”, M. A. de Carvalho Servia, I. O. Sandoval, K. K. Hii, K. Hellgardt, D. Zhang, E. A. del Rio Chanona, Digital Discovery, 2024, 3, 954-968. DOI: 10.1039/D3DD00212H.
“A Comparative Study of Transient Flow Rate Steps and Ramps for the Efficient Collection of Kinetic Data”, L. Schrecker, J. Dickhaut, C. Holtze, P. Staehle, M. Vranceanu, A. Wieja, K. Hellgardt and K. K. Hii, React. Chem. Eng. 2024, 9, 1077-1086. DOI: 10.1039/d3re00696d.
“Using the colloidal method to prepare Au catalysts for the alkylation of aniline by benzyl alcohol”, L. V. Hare, F. Parveen, J. Cookson, P. Ellis, K. Hellgardt, K. K. Hii, Int. J. Mol. Sci. 2023, 24, 14779. DOI: 10.3390/ijms241914779.
“Efficient multiparameter method for the collection of chemical reaction data via ‘one-pot’ transient flow”, L. Schrecker, J. Dickhaut, C. Holtze, P. Staehle, A. Wieja, K. Hellgardt, K. K. Hii, React. Chem. Eng. 2023, 8, 3196-3202. DOI: 10.1039/D3RE00439B.
“A Flash Thermal Racemization Protocol for the Chemoenzymatic Dynamic Kinetic Resolution and Stereoinversion of Chiral Amines”, M. J. Takle, B. J. Deadman, K. Hellgardt, J. Dickhaut, A. Weija, K. K. Hii, ACS Catal. 2023, 13, 10541-6. DOI: 10.1021/acscatal.3c02859.
“Mass transport of Diazomethane across Teflon AF2400 membrane for scale-up development”, F. Horvath-Gerber, K. K. Hii, C. Holtze, E. J. C. Deublein, K. Hellgardt, Org. Process Res. Dev. 2023, 27, 899-909. DOI: 10.1021/acs.oprd.3c00023.
“Homeopathic Palladium Catalysis? The observation of distinct kinetic regimes in a ‘ligandless’ Heck reaction at (ultra-)low catalyst loadings”, O. J. Newton, J. Richardson, K. Hellgardt, K. K. Hii, J. Catal. 2023, 424, 29-38. DOI: 10.1016/j.jcat.2023.05.005.
“Discovery of unexpectedly complex reaction pathways for the Knorr pyrazole synthesis via transient flow”, L. Schrecker, J. Dickhaut, Christian Holtze, P. Staehle, M. Vranceanu, K. Hellgardt, K. K. Hii, React. Chem. Eng. 2023, 8, 41-46. DOI: 10.1039/D2RE00271J.
“From hemoglobin to single-site hydrogenation catalyst”, A. Y. Li, J. Feng, A. Pedersen, H. Luo, J. Barrio, J. Roman, K. K. Hii, M. M. Titirici, Green Chem. 2022, 24, 7574-7583, DOI: 10.1039/D2GC02344J.
“Assessing a Sustainable Manufacturing Route to Lapatinib”, R. T. Stark, D. R. Pye, W. Chen, O. J. Newton, B. J. Deadman, P. W. Miller, J-L. Panayides, D. L. Riley, K. Hellgardt, K. K. Hii, React. Chem. Eng. 2022, 7, 2420-2426, DOI: 10.1039/D2RE00267A.
“On-demand, in situ generation of ammonium caroate (peroxymonosulfate) for the dihydroxylation of alkenes to vicinal diols”, B. J. Deadman, S. Gian, V. E. Y. Lee, L. A. Adrio, K. Hellgardt and K. K. Hii, Green Chem. 2022, 24, 5570-5578, DOI: 10.1039/D2GC00671E.
“Rapid formation of 2-lithio-1-(triphenylmethyl)imidazole and its substitution reactions in flow”, S. Wang, J-L. Panayides, D. Riley, C. Tighe, K. Hellgardt, K. K. Hii, P. Miller, React. Chem. Eng. 2021, 6, 2018-2023, DOI: 10.1039/D1RE00343G.
“Revisiting the mechanism of the Fujiwara-Moritani reaction”, C. J. Mulligan, J. S. Parker and K. K. Hii, React. Chem. Eng. 2020, 5, 1104-1111, DOI: 10.1039/D0RE00133C.
"Pd-LaFeO3 catalysts in aqueous ethanol: Pd reduction, leaching, and structural transformations in the presence of a base", S. Checchia, C. J. Mulligan, H. Emerich, I. Alxneit, F. Krumeich, M. Di Michiel, P. B. J. Thompson, K. K. Hii, D. Ferri, and M. A. Newton, ACS Catal. 2020, 10, 3933-3944, DOI: 10.1021/acscatal.9b04869.
Selected as ‘one of the most exciting subjects investigated at the ESRF’ - ESRF Highlights 2020 (page 142).
“In situ study of metal leaching from Pd/Al2O3 induced by K2CO3”, M. A. Newton, D. Ferri, C. J. Mulligan, I. Alxneit, H. Emerich, P. B. J. Thompson and K. K. Hii, Cat. Sci. Tech. 2020, 10, 466−474, DOI: 10.1039/C9CY02121C
"Peracetic acid as an atom-efficient reagent for directed C-H acetoxylation of arenes”, C. J. Mulligan, S. Bagale, O. Newton, J. S. Parker and K. K. Hii, ACS Sus. Chem. Eng. 2019, 7, 1611−1615, DOI: 10.1021/acssuschemeng.8b05370
“Base-free, tunable, Au-catalyzed oxidative esterification of alcohols in continuous flow”, F. J. Roberts, C. Richard, F. W. Zemichael, K. K. Hii, K. Hellgardt, C. Brennan and D. Sale, React. Chem. Eng. 2018, 3, 942 - 948, DOI: 10.1039/C8RE00085A
“Catalysis in flow: Nickel-catalyzed synthesis of primary amines from alcohols and NH3”, A. Y. K. Leung, K. Hellgardt and K. K. Hii, ACS Sus. Chem. Eng. 2018, 6, 5479-5484. DOI: 10.1021/acssuschemeng.8b00338
“2-Iodoxybenzoic Acid Synthesis by Oxidation of 2-Iodobenzoic Acid at a Boron-Doped Diamond Anode”, T. Bystron, A. Horbenko, K. Syslova, K. K. Hii, K. Hellgardt and G. Kelsall, ChemElectroChem 2018, 5, 1002-1005. DOI: 10.1002/celc.201800027
“Spatial, temporal and quantitative assessment of catalyst leaching in continuous flow”, E. M. Barreiro, Z. Hao, L. A. Adrio, J. R. van Ommen, K. Hellgardt and K. K. Hii, Catal. Today 2018, 308, 64-70, DOI: 10.1016/j.cattod.2017.10.013
“A colorimetric method for rapid and selective quantification of peroxodisulfate, peroxomonosulfate and hydrogen peroxide”, B. J. Deadman, K. Hellgardt and K. K. Hii, React. Chem Eng. 2017, 2, 462–466, DOI: 10.1039/C7RE00050B
“Effect of retained chlorine in ENCAT™ 30 catalysts on the development of encapsulated Pd: insights from in situ Pd K, L3 and Cl K-edge XAS”, M.. A. Newton, R. Nicholls, J. B. Brazier, B. N. Nguyen, C. J. Mulligan, K. Hellgardt, E. Barreiro, H. Emerich, K. K. Hii, I. Snigireva and P. B. J. Thompson, Catal. Struct. React. 2017, 3, 149-156, DOI: 10.1080/2055074X.2017.1348711
“Solvent–dependent nuclearity, geometry and catalytic activity of [(SPhos)Pd(Ph)Cl]2”, J. B. Brazier, M. A. Newton, E. M. Barreiro, L. A. Adrio, L. Naya, and K. K. Hii, Dalton Trans. 2017, 46, 7223–7231. DOI: 10.1039/c7dt01019b
“Controlled multiphase oxidations for continuous manufacturing of fine chemicals”, K. N. Loponova, B. J. Deadman, J. Zhu, C. Reilly, R. G. Holdich, K. K. Hii, K. Hellgardt, Chem. Eng. J. 2017, 329, 220-230. DOI: 10.1016/j.cej.2017.05.017
“Catalysis in flow: O2 effect on the catalytic activity of Ru(OH)x/Al2O3 during the aerobic oxidation of an alcohol”, J. B. Brazier, K. Hellgardt, and K. K. Hii, React. Chem. Eng. 2017, 2, 60–67. DOI: 10.1039/c6re00208k
“Effects of Cl on the reduction of supported PdO in ethanol/water mixtures”, J. B. Brazier, M. A. Newton, E. M. Barreiro, S. Parry, L. A. Adrio, C. J. Mulligan, K. Hellgardt, K. K. Hii, P. B. J. Thompson, R. Nichols, B. N. Nguyen, Catal. Struct. React. 2017, 3, 54–62. DOI:10.1080/2055074X.2016.1267296
“Restructuring of supported Pd by ‘green’ solvents: an operando Quick EXAFS (QEXAFS) study and implications for the derivation of structure–function relationships in Pd catalysis”, M. A. Newton, J. B. Brazier, E. M. Barreiro, H. Emerich, L. A. Adrio, C. J. Mulligan, K. Hellgardt, and K. K. Hii, Cat. Sci. Tech. 2016, 6, 8525–8531. DOI: 10.1039/C6CY02073A
“Synthesis of isoindolinones by Pd–catalyzed coupling between N–methoxybenzamide and styrene derivatives”, C. Xia, A. J. P. White and K. K. Hii, J. Org. Chem. 2016, 81, 7931–7938. DOI: 10.1021/acs.joc.6b01696
“Synthesis, structure and catalytic activity of NHC–Ag(I) carboxylate complexes”, V. H. L. Wong, S. V. C. Vummaleti, L. Cavallo, A. J. P. White, S. P. Nolan, and K. K. Hii, Chem. Eur. J. 2016, 22, 13320–13327. DOI: 10.1002/chem.201601762
“Goldilocks effect of water in Lewis–Brønsted Acid and Base catalysis”, B. J. Baron, W. T. Wong, P. Chiu and K. K. Hii, ACS Catal. 2016, 6, 4189–4194. DOI: 10.1021/acscatal.6b00800
“Towards a green generation of oxidant on demand: Practical electro–synthesis of ammonium persulfate”, J. Zhu, K. K. Hii, and K. Hellgardt, ACS Sustainable Chem. Eng. 2016, 4, 2027–2036. DOI: 10.1021/acssuschemeng.5b01372
“Operando XAFS of supported Pd nanoparticles in flowing ethanol/water mixtures: implications for greener catalysis”, M. A. Newton, J. B. Brazier, E. M. Barreiro, C. J. Mulligan, S. Parry, H. Emmerich, L. A. Adrio, K. Hellgardt and K. K. Hii, Green Chem. 2016, 18, 406–411. DOI: 10.1039/c5gc01600b
“Structure and bonding of [(NHC)AgX] (X = Cl, Br, I and OTf)”, V. H. L. Wong, A. J. P. White, T. S. A. Hor and K. K. Hii, Chem. Commun. 2015, 51, 17752–17755. DOI: 10.1039/c5cc07977b
“Electronic structures of cyclometalated palladium complexes in the higher oxidation states”, B. N. Nguyen, L. A. Adrio, T. Albrecht, A. J. P. White, M. A. Newton, M. Nachtegaal, S. J. A. Figueroa, and K. K. Hii, Dalton Trans. 2015, 44, 16586 – 16591. DOI: 10.1039/c5dt02104a
“Silver–catalyzed cyclisation of propargylic amides to oxazolines”, V. H. L Wong, A. J. P. White, T. S. A. Hor and K. K. Hii, Adv. Synth. Catal. 2015, 357, 3943–3948. DOI: 10.1002/adsc.201500610
“Ligand Effect and Control of E– and Z–Selectivity in the silver–catalyzed synthesis of 4–bromooxazolines”, V. H. L. Wong, A. J. P. White, T. S. A. Hor and K. K. Hii, Adv. Synth. Catal. 2015, 357, 2485–2491. DOI: 10.1002/adsc.201500157
Chosen by reviewers as a ‘Very Important Publication’
“Chemo– and diastereo–selectivities in the electrochemical reduction of maleimides”, K. Rix, G. H. Kelsall, K. Hellgardt and K. K. Hii, ChemSusChem 2015, 8, 665–671. DOI: 10.1002/cssc.201403184
“Atropisomeric [(diphosphine)Au2Cl2] complexes and their catalytic activity towards asymmetric cycloisomerisation of 1,6–enynes”, E. M. Barreiro, E. V. Boltukhina, A. J. P. White and K. K. Hii, Chem. Eur. J. 2015, 21, 2686–2690. DOI: 10.1002/chem.201404496
Chosen as a ‘Hot Paper’.
“Catalysis in flow: Operando study of Pd catalyst speciation and leaching”, J. B. Brazier, B. N. Nguyen, L. A. Adrio, E. M. Barreiro, W. P. Leong, M. A. Newton, S. J. A. Figueroa, K. Hellgardt and K. K. Hii, Catal. Today 2014, 229, 95–103. DOI: 10.1016/j.cattod.2013.10.079
“Silver–catalysed intramolecular hydroamination of alkynes with trichloroacetimidate”, V. H. L. Wong, T. S. A. Hor and K. K. Hii, Chem. Commun. 2013, 49, 9272–9274. DOI: 10.1039/c3cc45500a
“Methylene–bridged bis(imidazoline)–derived 2–oxopyrimidinium salts as catalysts for asymmetric Michael reactions”, A. E. Sheshenev, E. V. Boltukhina, A. J. P. White and K. K. Hii, Angew. Chem. Int. Ed. 2013, 52, 6988–6991. DOI: 10.1002/anie.201300614
“New chiral zwitterionic phosphorus heterocycles: Synthesis, structure, properties and application as chiral solvating agents”, A. E. Sheshenev, E. V. Boltukhina, A. A. Grishina, I. Cisařova, I. M. Lyapkalo and K. K. Hii, Chem. Eur. J. 2013, 19, 8136–8143. DOI: 10.1002/chem.201300062
“Levonantradol: asymmetric synthesis and structural analysis”, A. E. Sheshenev, E. V. Boltukhina and K. K. Hii, Chem. Commun. 2013, 49, 3685–3687. DOI: 10.1039/c3cc41388h
“Preparation of dicationic palladium complexes for asymmetric reactions”, A. E. Sheshenev, A. M. R. Smith and K. K. Hii, Nature Protocols 2012, 7, 1765–1773. DOI: 10.1038/nprot.2012.095
“Silver–catalysed enantioselective additions of O–H and N–H to allenes: A new model for stereoselectivity based on non–covalent interactions”, J. L. Arbour, H. S. Rzepa, J. Contreras–García, L. A. Adrio, E. M. Barreiro, and K. K. Hii, Chem. Eur. J. 2012, 18, 11317–11324. DOI: 10.1002/chem.201200547
“Gold(I) complexes of conformationally constricted chiral ferrocenyl phosphines”, E. M. Barreiro, D. F. D. Broggini, L. A. Adrio, A. J. P. White, R. Schwenk, A. Togni and K. K. Hii, Organometallics 2012, 31, 3745–3754. DOI: 10.1021/om300222k
“Asymmetric synthesis of 2–alkyl–substituted tetrahydroquinolines by an enantioselective aza–Michael reaction”, L. L. Taylor, F. W. Goldberg and K. K. Hii, Org. Biomol. Chem. 2012, 10, 4424–4432. DOI: 10.1039/c2ob25122a
“Deconvolution of the mechanism of homogeneous gold–catalyzed reactions”, B. N. Nguyen, L. A. Adrio, E. M. Barreiro, J. B. Brazier, P. Haycock, K. K. Hii, M. Nachtegaal, M. A. Newton and J. Szlachetko, Organometallics 2012, 31, 2395–2402. DOI: 10.1021/om300030e
“Catalysis in flow: Au–catalysed alkylation of amines by alcohols”, N. Zotova, F. J. Roberts, G. H. Kelsall, A. S. Jessiman, K. Hellgardt, and K. K. Hii, Green Chem. 2012, 14, 226–232. DOI: 10.1039/c1gc16118k
“Speciation of Pd(OAc)2 in ligandless Suzuki–Miyaura reactions”, L. A. Adrio, B. N. Nguyen, G. Guilera, A. G. Livingston and K. K. Hii, Cat. Sci. Tech. 2012, 2, 316–323. DOI: 10.1039/c1cy00241d
“Alternative to benzoquinone for room–temperature Fujiwara–Moritani reactions”, X. Liu and K. K. Hii, J. Org. Chem. 2011, 76, 8022–8026. DOI: 10.1021/jo201164m
“An expedient synthesis of olfactory lactones by intramolecular hydroacylalkoxylation reactions”, L. A. Adrio and K. K. Hii, Eur. J. Org. Chem. 2011, 1852–1857. DOI: 10.1002/ejoc.201001556
“Catalysis in flow: practical and selective aerobic oxidation of alcohols”, N. Zotova, K. Hellgardt, G. H. Kelsall, A. S. Jessiman and K. K. Hii, Green Chem. 2010, 12, 2157–2163. DOI: 10.1039/c0gc00493f
“Oxidative amidation of activated alkenes using Pd(OAc)2 as a catalyst precursor”, X. Liu and K. K. Hii, Eur. J. Org. Chem. 2010, 5181–5189. DOI: 10.1002/ejoc.201000384
“Delineating origins of stereocontrol in Pd–catalyzed asymmetric alpha–hydroxylation of beta–ketoesters”, A. M. R. Smith, H. S. Rzepa, A. J. P. White, D. Billen and K. K. Hii, J. Org. Chem. 2010, 75, 3085–3096. DOI: 10.1021/jo1002906
“Copper–catalysed intramolecular O–H addition to unactivated alkenes”, L. A. Adrio, L. S. Quek, J. G. Taylor and K. K. Hii, Tetrahedron 2009, 65, 10334–10338. DOI: 10.1016/j.tet.2009.10.055
“Unusual regiodivergence in metal–catalysed intramolecular cyclisation of g–allenols”, J. L. Arbour, H. S. Rzepa, A. J. P. White and K. K. Hii, Chem. Commun. 2009, 7125–7127. DOI: 10.1039/b913295c
“Palladium–catalysed enantioselective alpha–hydroxylation of beta–ketoesters”, A. M. R. Smith, D. Billen and K. K. Hii, Chem. Commun. 2009, 3925–3927. DOI: 10.1039/b907151b
“Delineating ligand effects in intramolecular aryl amidation reactions: formation of a novel spiro–heterocycle by a tandem cyclisation process”, E. L. Cropper, A. P. Yuen, A. J. P. White, A. Ford and K. K. Hii, Tetrahedron 2009, 65, 525–530. DOI: 10.1016/j.tet.2008.10.098
“A recyclable copper(II) catalyst for the annulation of phenols with 1,3–dienes”, L. A. Adrio and K. K. Hii, Chem. Commun. 2008, 2325–2327. DOI: 10.1039/b719465j
“A practical and general synthesis of unsymmetrical terphenyls by tandem Suzuki–Miyaura coupling reactions”, J. M. A. Miguez, L. A. Adrio, A. Sousa–Pedrares, J. M. Vila, and K. K. Hii, J. Org. Chem. 2007, 72, 7771–7774. DOI: 10.1021/jo701308b
“Preparation of Macrocyclon analogues: calix[8]arenes with extended polyethylene glycol chains”, F. A. Loiseau, A. M. Hill and K. K. Hii, Tetrahedron 2007, 63, 9947–9959. DOI: 10.1016/j.tet.2007.07.057
“A concise asymmetric synthesis of torcetrapib”, M. Guinó, P. H. Phua, J–C. Caille and K. K. Hii, J. Org. Chem. 2007, 72, 6290–6293. DOI: 10.1021/jo071031g
“Elucidating the mechanism of the asymmetric aza–Michael reaction”, P. H. Phua, S. P. Mathew, A. J. P. White, J. G. de Vries, D. G. Blackmond and K. K. Hii, Chem. Eur. J. 2007, 13, 4602–4613. DOI: 10.1002/chem.200601706
“In situ investigation of the oxidative addition in homogeneous Pd catalysts by synchronised time resolved UV–Vis/XAFS”, G. Guilera, M. A. Newton, C. Polli, M. Guinó and K. K. Hii, Chem. Commun. 2006, 4306–4309. DOI: 10.1039/b606772g
“Copper–catalyzed intermolecular hydroamination of alkenes”, J. G. Taylor, N. Whittall and K. K. Hii, Org. Lett. 2006, 8, 3561–3564. DOI: 10.1021/ol061355b
“Enabling ligand screening for Pd–catalysed enantioselective aza–Michael addition reactions”, P. H. Phua, J. G. de Vries and K. K. Hii, Adv. Synth. Catal. 2006, 348, 587–592. DOI: 10.1002/adsc.200505404
“Practical synthesis of chiral vinylphosphine oxides by direct nucleophilic substitution. stereodivergent synthesis of aminophosphine ligands”, M. Oliana, F. King, P. N. Horton, M. B. Hursthouse and K. K. Hii, J. Org. Chem. 2006, 71, 2472–2479. DOI: 10.1021/jo052575q
“Ligand effects in the synthesis of N–heterocycles by intramolecular Heck reactions”, E. L. Cropper, A. J. P. White, A. Ford and K. K. Hii, J. Org. Chem. 2006, 71, 1732–1735. DOI: 10.1021/jo0522660
“Palladium–catalysed enantioselective conjugate addition of aromatic amines to alpha,beta–unsaturated N–imides. Effect of the chelating moiety”, P. H. Phua, J. G. de Vries and K. K. Hii, Adv. Synth. Catal. 2005, 347, 1775–1780. DOI: 10.1002/adsc.200505126
“Synthesis of P–chirogenic diarylphosphinoacetic acids and their proline derivatives for palladium–catalysed allylic alkylation reactions”, H. Lam, S. J. Coles, M. B. Hursthouse, D. J. Aldous and K. K. Hii, Tetrahedron Lett. 2005, 46, 8145–8148. DOI: 10.1016/j.tetlet.2005.09.136
“Copper(II)–catalysed addition of O–H bonds to norbornene”, J. G. Taylor, N. Whittall and K. K. Hii, Chem. Commun. 2005, 5103–5105. DOI: 10.1039/b509933a
“Recyclable polymer–supported Pd catalysts for aryl amination reactions”, M. Guinó and K. K. Hii, Tetrahedron Lett. 2005, 46, 7363–7366. DOI: 10.1016/j.tetlet.2005.08.122
“Reversal of aryl bromide reactivity in palladium–catalysed aryl amination reactions catalysed by an aminophosphine ligand”, S. L. Parisel, L. A. Adrio, A. A. Pereira, M. M. Pérez, J. M. Vila and K. K. Hii, Tetrahedron, 2005, 61, 9822–9826. DOI: 10.1016/j.tet.2005.06.073
“Phosphine–functionalised polymer resins as Pd scavengers”, M. Guinó and K. K. Hii, Tetrahedron Lett. 2005, 46, 6911–6913. DOI: 10.1016/j.tetlet.2005.08.005
“Wang–aldehyde resin as a recyclable support for the synthesis of alpha, alpha–disubstituted amino acid derivatives”, M. Guinó and K. K. Hii, Org. Biomol. Chem. 2005, 3, 3188–3193. DOI: 10.1039/b505881c
“Enantioselective addition of amines to alkenoyl–N–oxazolidinones”, P. H. Phua, K. Li and K. K. Hii, Tetrahedron 2005, 61, 6237–6242. DOI: 10.1016/j.tet.2005.03.125
“Polymer–supported manganese porphyrin catalysts – peptide–linker promoted stability”, E. Brulé, K. K. Hii and Y. R. de Miguel, Org. Biomol. Chem. 2005, 3, 1971–1976. DOI: 10.1039/b502149a
“Conformation analyses, dynamic behavior and amide bond distortions of medium–sized heterocycles. 2. Partially and fully reduced 1–benzazocines, benzazonines and benzoazecines”, M. Qadir, J. Cobb, A. J. P. White, P. W. Sheldrake, N. Whittall, K. K. Hii, P. N. Horton and M. B. Hursthouse, J. Org. Chem. 2005, 70, 1552–1557. DOI: 10.1021/jo048117j
“Conformation analyses, dynamic behavior and amide bond distortions of medium–sized heterocycles. 1. Partially and fully reduced 1–benzazepines”, M. Qadir, J. Cobb, A. J. P. White, P. W. Sheldrake, N. Whittall, K. K. Hii, P. N. Horton and M. B. Hursthouse, J. Org. Chem. 2005, 70, 1545–1551. DOI: 10.1021/jo048118b
“Aminohydroxy phosphine oxide ligands in ruthenium–catalysed asymmetric transfer hydrogenation reactions”, X. Cheng, P. N. Horton, M. B. Hursthouse and K. K. Hii, Tetrahedron Asymmetry 2004, 15, 2241–2246. DOI: 10.1016/j.tetasy.2004.04.040
“Chemoselective epoxidation of dienes using polymer–supported manganese porphyrin catalysts”, E. Brulé, Y. R. de Miguel and K. K. Hii, Tetrahedron 2004, 60, 5913–5918. DOI: 10.1016/j.tet.2004.05.026
“Mixed donor aminophosphine oxide ligands in ruthenium–catalysed asymmetric transfer hydrogenation reactions”, M. S. Rahman, M. Oliana and K. K. Hii, Tetrahedron Asymmetry 2004, 15, 1835–1840. DOI: 10.1016/j.tetasy.2004.05.001
“Asymmetric synthesis of b–amino acid and amide derivatives via catalytic conjugate addition of aromatic amines to N–alkenoyl carbamates”, K. Li, X. Cheng and K. K. Hii, Eur. J. Org. Chem. 2004, 959–964. DOI: 10.1002/ejoc.200300740
Most frequently downloaded Short Communications 2004
“Phosphorus–Nitrogen–Phosphorus ligands: cooperative effects between nitrogen and phosphorus substituents on catalytic activity”, S. L. Parisel, N. D. Moorcroft, A. Jutand, D. J. Aldous and K. K. Hii, Org. Biomol. Chem. 2004, 2, 301–306. DOI: 10.1039/b312702h
“Multigram synthesis of well–defined extended bifunctional polyethylene glycol chains”, F. A. Loiseau, A. M. Hill and K. K. Hii, J. Org. Chem. 2004, 69, 639–647. DOI: 10.1021/jo035042v
“Unsymmetrical terdentate phosphorus–nitrogen–nitrogen (PNN) ligands: effect of the M/L ratio and the pendant group on stereoselectivity”, X. Cheng and K. K. Hii, Tetrahedron Asymmetry 2003, 14, 2045–2052. DOI: 10.1016/S0957–4166(03)00361–6
“Mild reduction of chlorophosphine boranes to secondary phosphine boranes”, H. Lam, D. J. Aldous and K. K. Hii, Tetrahedron Lett. 2003, 44, 5213–5216. DOI: 10.1016/S0040–4039(03)01225–5
“Dicationic [(BINAP)Pd(solvent)2]2+[TfO–]2: enantioselective hydroamination catalyst for alkenoyl–N–oxazolidinones”, K. Li and K. K. Hii, Chem. Commun. 2003, 1132–1133. DOI: 10.1039/b302246c
Top 10 most accessed article for May 2003
“Synthesis of 2–substituted 1–benzyl–2,3,4,5–tetrahydro–1–benzazepines by palladium catalysis. observation of a competitive beta–hydride elimination pathway”, M. Qadir, R. E. Priestley, T. W. D. F. Rising, T. Gelbrich, S. J. Coles, M. B. Hursthouse, P. W. Sheldrake, N. Whittall and K. K. Hii, Tetrahedron Lett. 2003, 44, 3675–3678. DOI: 10.1016/S0040–4039(03)00676–2
“Air– and moisture– stable cationic (diphosphine)palladium(II) complexes as hydroamination catalysts. X–ray crystal structures of two [(diphosphine)Pd(NCMe)(OH2)]2+[OTf]–2 complexes”, K. Li, P. N. Horton, M. B. Hursthouse and K. K. Hii, J. Organometallic Chem. 2003, 665, 250–257. DOI: 10.1016/S0022–328X(02)02138–1
“Coordination chemistry and catalytic activity of ruthenium complexes of terdentate Phosphorus–Nitrogen–Phosphorus (PNP) and bidentate Phosphorus–Nitrogen (PNH) ligands”, M. S. Rahman, P. D. Prince, J. W. Steed and K. K. Hii, Organometallics 2002, 21, 4927–4933. DOI: 10.1021/om0201314
“Examining the effect of hemilabile donor groups in non–C2 symmetrical terdentate ligands”, H. Lam, X. Cheng, J. W. Steed, D. J. Aldous and K. K. Hii, Tetrahedron Lett. 2002, 43, 5875–5877. DOI: 10.1016/s0040-4039(02)00988-7
“Palladium–catalysed addition of R2NH to double bonds. Synthesis of alpha–amino tetrahydro–furan and pyran rings”, X. H. Cheng and K. K. Hii, Tetrahedron 2001, 57, 5445–5450. DOI: 10.1016/S0040–4020(01)00446–X
“Examination of ligand effects in the Heck arylation reaction”, M. Qadir, T. Möchel and K. K. Hii, Tetrahedron 2000, 56, 7975–7979. DOI: 10.1016/S0040-4020(00)00703-1
“Scope and limitations of the preparation of aminophosphines R–NH(CH2CH2PPh2) and aminodiphosphines R–N(CH2CH2PPh2)2 via Michael addition of amines to vinylphosphines”, M. S. Rahman, J. W. Steed and K. K. Hii, Synthesis 2000, 1320–1326. DOI: 10.1055/s-2000-6422
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